Das Institut für Integrative und Experimentelle Genomik stellt sich vor.

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    24-Jun-2015

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Das Institut fr Integrative und Experimentelle Genomik der Universitt zu Lbeck stellt sich vor.

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  • 1. Todesursache Nummer 1 in der westlichen Welt 200.000 Herzinfarkttote in Deutschland/Jahr

2. 3. 4. 5. 6. Two risk variants 7. Two normal variants Two risk variants 8. 3 6M + 3 6 M + 6-8 M + 3-4 M + 12 M + 6-8 M + 10-14 M + 6-12 M Gene Symbol KO Vector KO ESC Chimera Founder Backcross to B6 Intercross GMC Backcross to Apoe /Ldlr Phenotyping Atherosc / Neointima Cxcl12 --- --- --- --- --- lethal Gucy1A3 --- --- --- --- --- Done in progress in progress Mras --- --- --- --- Done Done in progress Done in progress Adamts7 --- Done Done --- Done in progress in progress in progress Cyp17a1 --- Done Done --- Done in progress in progress Ppap2b --- Done Done --- lethal Zc3hc1 --- Done Done --- Done in progress in progress in progress Phactr1 Done Done in progress 9.